Carbon dioxide storage is an effective method for utilizing greenhouse gas and reducing greenhouse gas discharge. Nevertheless, escape of carbon dioxide through cap rock after sequestration will cause disasters such as upheaving or sinking of the ground surface, water pollution, breakage of oceanic ecosystem, greenhouse effect et al. In this paper, research advances on carbon dioxide storage and escape is summarized in significance. Three important storage forms are introduced, furthermore, escape form of carbon dioxide and key parameters are analyzed. It is shown that two important problems are needed to investigate further: (1) basic parameters in carbon dioxide escape are needed to determined by model experiments. (2) models of multi-phase flow considering chemical reaction, stratum characteristics, well distribution characteristics are needed considered. (3) not only diffusion and seepage, but also increase of seepage due to well distribution and crack formation by high gas pressure are needed to consider.