Advance from biomechanics to mechanobiology

JIANG Z l

doi:10.6052/1000-0992-16-023

Volume 47 Issue 1

Feb. 2017

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Article Navigation > Advances in Mechanics > 2017 > 47(1): 309-332

JIANG Z l. Advance from biomechanics to mechanobiology[J]. Advances in Mechanics, 2017, 47(1): 309-332. doi: 10.6052/1000-0992-16-023

Citation:

JIANG Z l. Advance from biomechanics to mechanobiology[J]. Advances in Mechanics, 2017, 47(1): 309-332. doi: 10.6052/1000-0992-16-023

JIANG Z l. Advance from biomechanics to mechanobiology[J]. Advances in Mechanics, 2017, 47(1): 309-332. doi: 10.6052/1000-0992-16-023

Citation:

JIANG Z l. Advance from biomechanics to mechanobiology[J]. Advances in Mechanics, 2017, 47(1): 309-332. doi: 10.6052/1000-0992-16-023

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Advance from biomechanics to mechanobiology

doi: 10.6052/1000-0992-16-023

JIANG Z l^,

Institute of Mechanobiology & Medical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China

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Corresponding author: JIANG Z l
Received Date: 2016-06-27
Rev Recd Date: 2016-10-26

Available Online: 2016-11-20

Publish Date: 2017-02-24

Abstract

Abstract

In the present paper, we introduce the development of biomechanics and the contribution of Dr. Y. C. Fung, the concept and development of mechanobiology, the development of biomechanics, as well as the advance of mechanobiology in China. We reflect the current status and progress from biomechanics to mechanobiology, and further prospect the vision of biomechanics in China.
- biomechanics,
- mechanobiology,
- stress-growth,
- remodeling,
- mechanotransduction

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致谢: 国家自然科学基金资助项目(11232010,11229202,11625209,31670958).在本文撰写过程中得到了中国科学院力学研究所陶祖莱研究员的指正;军事医学科学院卫生装备研究所张西正研究员、重庆大学杨力教授与王贵学教授、四川大学李良教授、清华大学冯西桥教授、上海交通大学房兵教授和电子科技大学刘贻尧教授提供了部分研究结果特此一并感谢！

References(82)

References

[1]	邓小燕, 王贵学. 2002. 动脉系统中致动脉粥样性脂质的浓度极化现象. 中国科学, 32: 559-67 http://www.cnki.com.cn/Article/CJFDTOTAL-JCXK200206011.htm
[2]	陈槐卿. 1980. 血液流变学及其临床应用. 成都: 四川教育出版社
[3]	冯元帧. 1983. 生物力学. 北京: 科学出版社
[4]	冯元帧. 1986a. 生物力学——活组织的力学特性. 戴克刚, 鞠烽炽, 译. 长沙: 湖南科学技术出版社.
[5]	冯元帧. 1986b. 生物动力学——血液循环. 戴克刚, 译. 长沙: 湖南科学技术出版社.
[6]	冯元帧. 1993. 生物力学——运动、流动、应力和生长. 邓善熙, 译. 成都: 四川教育出版社.
[7]	姜宗来. 2006. 心血管力学生物学研究的新进展. 医用生物力学, 21: 251-253 http://www.cnki.com.cn/Article/CJFDTOTAL-YISX200604000.htm Jiang Z L. 2006. Recent advances in cardiovascular mechanobiology. J Med Biomech, 21: 251-253 http://www.cnki.com.cn/Article/CJFDTOTAL-YISX200604000.htm
[8]	姜宗来, 樊瑜波. 2010. 生物力学——从基础到前沿. 北京: 科学出版社 Jiang Z L, Fan Y B. 2010. Biomechanics. Beijing: Science Press
[9]	姜宗来. 2011. 我国生物力学研究现状与展望. 中国生物医学工程学报, 30: 165-172 http://www.cnki.com.cn/Article/CJFDTOTAL-ZSWY201102002.htm Jiang Z L. The recent advances and prospects of biomechanics in China. Chinese J Biomed Eng, 30: 165-172 http://www.cnki.com.cn/Article/CJFDTOTAL-ZSWY201102002.htm
[10]	柳兆荣, 李惜惜. 1998. 血液动力学原理和方法. 上海: 复旦大学出版社
[11]	陶祖莱. 1984. 生物流体力学. 北京: 科学出版社
[12]	陶祖莱. 2000. 生物力学导论. 天津: 天津科技翻译出版社公司.
[13]	王以进. 1989. 骨科生物力学. 北京: 人民军医出版社
[14]	翁文良, 廖福龙, 吴云鹏. 1989. 血液流变学研究方法及其应用. 北京: 科学出版社
[15]	吴云鹏, 杨瑞芳. 1987. 体液流变特性. 北京: 科学出版社.
[16]	吴云鹏. 1993. 胆道流变学. 重庆: 重庆出版社
[17]	Yang G T,Wu W Z. 1989. Bone Mechanics. Beijing:Science Press
[18]	杨桂通. 1990. 医用生物力学. 北京: 科学出版社 Yang G T. 1990. Medical Biomechanics. Beijing:Science Press
[19]	Cheng B B, QuMJ,Wu L L, et al. 2014. MicroRNA-34a targets Forkhead Box J2 to modulate differentiation of endothelial progenitor cell in response to shear stress. J Mol Cell Cardio, 74: 4-12
[20]	Cheng M, Liu X, Li Y, Tang R, Zhang W, Wu J, Li L, Liu X, Gang Y, Chen H. 2007. IL-8 gene induction by low shear stress: pharmacological evaluation of the role of signaling molecules. Biorheology, 44: 349-360
[21]	Cheng M, Guan X, Li H, Cui X D, Zhang X Y, Li X, Jing X, Wu H Y, Avsar E. 2013. Shear stress regulates late EPC differentiation via mechanosensitive molecule-mediated cytoskeletal rearrangement. Plos One, 8: e67675
[22]	Chien S, Usami S, Dellenback R L, Gregersen M I. 1967a. Blood Viscosity: Influence of erythrocyte defor-mation. Science, 157: 827-829
[23]	Chien S, Usami S, Dellenback R L, Gregersen MI, Nanninga LB, Guest MM. 1967b. Blood Viscosity:Influence of erythrocyte aggregation. Science, 157: 829-831
[24]	Chien S. 1970. Shear dependence of effective cell volume as a determinant of blood viscosity. Science, 168:977-978 doi: 10.1126/science.168.3934.977
[25]	Chien S. 2007. Mechanotrasduction and endothelial cell homeostasis: the wisdom of the cell. Am J Physiol Heart Circ Physiol, 292: H1209-H1224 http://cn.bing.com/academic/profile?id=808e6c7f57b55959ac808f8bd09c4ea6&encoded=0&v=paper_preview&mkt=zh-cn
[26]	Chiu J J, Usami S, Chien S. 2009. Vascular endothelial responses to altered shear stress: Pathologic implications for atherosclerosis. Ann Med, 41: 19-28 doi: 10.1080/07853890802186921
[27]	Du J, Chen X F, Liang X D, Zhang G, Xu J, He L, Zhan Q, Feng X Q, Chien S, Yang C. 2011. Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity. Proc Natl Acad Sci USA, 108: 9466-9471 doi: 10.1073/pnas.1106467108
[28]	Du J, Zu Y, Du S Y, Xu Y, Zhang L, Jiang L, Wang Z, Chien S, Yang C. 2016. Extracellular matrix stiffness dictates Wnt expression through integrin pathway. Sci Rep, 6: 20395 doi: 10.1038/srep20395
[29]	Engler A J, Sen S, Sweeney H L, Discher D E. 2006. Matrix elasticity directs stem cell lineage specification.Cell, 126: 677-689 doi: 10.1016/j.cell.2006.06.044
[30]	Fung Y C. 1981. Biomechanics: Mechanical Properties of Living Tissues. 2nd edn. Springer-Verlag New York Inc.
[31]	Fung Y C. 1984. Biodynamics: Circulation. Springer-Verlag New York Inc.
[32]	Fung Y C, Liu S Q. 1989. Change of residual stress in arteries due to hypertrophy caused by aortic constriction. Circ Res, 65: 1340-1349 doi: 10.1161/01.RES.65.5.1340
[33]	Fung Y C. 1990. Biomechanics: Motion, Flow, and Growth. Springer-Verlag New York Inc.
[34]	Fung Y C, Liu S Q. 1991. Changes of zero-stress state of rat pulmonary arteries in hypoxic hypertension. J Appl Physiol, 70: 2455-2470 doi: 10.1063/1.349398
[35]	Fung Y C. 1993. Biomechanics: Mechanical Properties of Living Tissues. 2nd edn. Springer-Verlag New York Inc.
[36]	Fung Y C. 1996. Biomechanics: Circulation. 2ed, Springer-Verlag New York Inc.
[37]	Fung Y C. 2002. Celebrating the inauguration of the journal: Biomechanics and modeling in mechanobiology. Biomechan Model Machanobiol, 1: 3-4 doi: 10.1007/s10237-002-0006-z
[38]	Gong H, Zhang M, Fan Y B, KwokWL, Leung P C. 2012. Relationships between femoral strength evaluated by nonlinear finite element analysis and BMD, material distribution and geometric morphology. Ann Biomed Eng, 40: 1575-1585.
[39]	Han Y, Wang L, Yao Q P, Zhang P, Liu B, Wang G L, Shen B R, Cheng B, Wang Y, Jiang Z L, Qi Y X. 2015. Nuclear envelope proteins Nesprin2 and LaminA regulate proliferation and apoptosis of vascular endothelial cells in response to shear stress. BBA Mol Cell Res, 1853: 1165-1173 https://www.researchgate.net/publication/272753862_Nuclear_envelope_proteins_Nesprin2_and_LaminA_regulate_proliferation_and_apoptosis_of_vascular_endothelial_cells_in_response_to_shear_stress?_sg=N9AKap9--TwcNP5SFWK8U_l1fkflvUJ9wk0SXRg1rVub7QmnThgx6wTfgp6mamVTZfl6miHI33jTX5dHTmS8hhPAW8tQ7RDxZ424HShnyjk
[40]	He M, Liang X, He L, Wen W, Zhao S, Wen L, Liu Y, Shyy J Y, Yuan Z. 2013. Endothelial dysfunction in rheumatoid arthritis: the role of monocyte chemotactic protein-1-induced protein. Arterioscler Thromb Vasc Biol, 33: 1384-1391. http://cn.bing.com/academic/profile?id=501562a8919d32da90b89e792249c628&encoded=0&v=paper_preview&mkt=zh-cn
[41]	Huang W, Sher Y P, Peck K, Fung Y C. 2002. Matching gene activity with physiological functions. Proc Natl Acad Sci USA, 99: 2603-2608.
[42]	Jiang J, Qi Y X, Zhang P, Gu W T, Yan Z Q, Shen B R, Yao Q P, Kong H, Chien S, Jiang Z L. 2013. Involvement of Rab28 in NF-кB nuclear transport in endothelial cells. Plos One, 8: e56076 doi: 10.1371/journal.pone.0056076
[43]	Jiang Z L, Kassab G S, Fung Y C. 1994. Diameter-defined strahler system and connectivity matrix of the pulmonary arterial tree. J Appl Physiol, 76: 882-892 https://www.researchgate.net/publication/15022865_Diameter-defined_Strahler_system_and_connectivity_matrix_of_the_pulmonary_arterial_tree
[44]	Kang H, Fan Y, Deng X. 2011. Vascular smooth muscle cell glycocalyx modulates shear-induced proliferation, migration, and no production responses. Am J Physiol Heart Circ Physiol, 300: H76-H83 doi: 10.1152/ajpheart.00905.2010
[45]	Kang H, Fan Y, Sun A, Jia X, Deng X. 2013. Simulated microgravity exposure modulates the phenotype of cultured vascular smooth muscle cells. Cell Biochem Biophys, 66: 121-130 doi: 10.1007/s12013-012-9460-0
[46]	Li H, Li R X, Wan Z M, Xu C, Li J Y, Hao Q X, Guo Y, Liu L, Zhang X Z. 2013. Counter-effect of constrained dynamic loading on osteoporosis in ovariectomized mice. J Biomech, 46: 1242-1247 doi: 10.1016/j.jbiomech.2013.02.016
[47]	Liu L, Guo Y, Chen X Z, Li R, Li Z, Wang L, Wan Z, Li J, Hao Q, Li H, Zhang X. 2012. Three-dimensional dynamic culture of pre-osteoblasts seeded in HA-CS/Col/nHAP composite scaffolds and treated with ff-ZAL. Acta Biochim Biophys Sin, 44: 669-677 doi: 10.1093/abbs/gms049
[48]	Li L, Qian Y, Jiang C, Lv Y, Liu W, et al. 2012. The use of hyaluronan to regulate protein adsorption and cell infiltration in nanofibrous scaffolds. Biomaterials, 33: 3428-3445 doi: 10.1016/j.biomaterials.2012.01.038
[49]	Li L, Puhl S, Meinel L, Germershaus O. 2014. Silk fibroin layer-by-layer microcapsules for localized gene delivery. Biomaterials, 35: 7929-7939 doi: 10.1016/j.biomaterials.2014.05.062
[50]	Li L, Zhang J, Xiong N, Li S, Chen Y, Yang H,Wu C K, Zeng H J, Liu Y Y. 2016a. Notch-1 signaling activates NF-kB in human breast carcinoma MDA-MB-231 cells via PP2A-dependent PI3K/AKT pathway. Med Oncol, 33: 1-11 doi: 10.1007/s12032-015-0714-8
[51]	Li S, Lu J, Chen Y, Xiong N, Li L, Zhang J, Yang H, Wu C, Zeng H, Liu Y. 2016b. MCP-1-triggered ERK/GSK-3beta/Snail pathway facilitates epithelial-mesenchymal transition and promotes cell migration of human breast carcinoma MCF-7 cells. Cell Mol Immunol, 13: 1-10 doi: 10.1038/cmi.2015.94
[52]	Li Y, Xu G K, Li B, Feng X Q. 2010. A molecular mechanisms-based biophysical model for two-phase cell spreading. Appl Phys Lett, 96: 043703 doi: 10.1063/1.3298361
[53]	Li Z J, Huang W, Jiang Z L, Gregersen H, Fung Y C. 2004. Tissue remodeling of rat pulmonary arteries in recovery from hypoxic hypertension. Proc Natl Acad Sci USA, 101: 11488-1149 doi: 10.1073/pnas.0404084101
[54]	Liu X, Fan Y, Deng X. 2011. Mechanotransduction of flow-induced shear stress by endothelial glycocalyx fibers is torque determined. ASAIO J, 57: 487-94 doi: 10.1097/MAT.0b013e318233b5ed
[55]	Liu X, Pu F, Fan Y, Deng X, Li D, Li S. 2009. A numerical study on the flow of blood and the transport of LDL in the human aorta: the physiological significance of the helical flow in the aortic arch. Am J Physiol Heart Circ Physiol, 297: H163-H170 doi: 10.1152/ajpheart.00266.2009
[56]	Liu Y, Tian XY, Mao G, Fang X, Fung ML, Shyy JY, Huang Y, Wang N. 2012. Peroxisome proliferator-activated receptor-fl ameliorates pulmonary arterial hypertension by inhibiting 5-hydroxytryptamine 2B receptor. Hypertension, 60: 1471-1478 doi: 10.1161/HYPERTENSIONAHA.112.198887
[57]	Luo Z, Jiang L, Xu Y, Li H, Xu W, Wu S, Wang Y, Tang Z, Lv Y, Yang L. 2015. Mechano growth factor(MGF) and transforming growth factor (TGF)-3 functionalized silk scaffolds enhance articular hyaline cartilage regeneration in rabbit model. Biomaterials, 52: 463-475 doi: 10.1016/j.biomaterials.2015.01.001
[58]	Qi Y X, Qu M J, Long D K, Liu B, Yao QP, Chien S, Jiang Z L. 2008. Rho-GDI alpha downregulated by low shear stress promotes vascular smooth muscle cell migration and apoptosis: A proteomic analysis. Cardiovasc Res, 80: 114-122 doi: 10.1093/cvr/cvn158
[59]	Qi Y X, Jiang J, Jiang X H, Wang X D, Ji SY, Han Y, Long D K, Shen B R, Yan Z Q, Chien S, Jiang Z L. 2011. Paracrine control of PDGF-BB and TGFfi1 on cross-talk between endothelial cells and vascular smooth muscle cells during low shear stress induced vascular remodeling. Proc Natl Acad Sci USA, 108:1908-1913 doi: 10.1073/pnas.1019219108
[60]	Qi Y X, Yao Q P, Huang K, et al. 2016. Nuclear envelope proteins modulate proliferantion of vascular smooth muscle cells during cyclic stretch application. Proc Natl Acad Sci USA, 113: 5293-5298 doi: 10.1073/pnas.1604569113
[61]	Qiu J, Peng Q, Zheng Y, Hu J, Luo X, Teng Y, Jiang T, Yin T, Tang C, Wang G. 2012. OxLDL stimulates Id1 nucleocytoplasmic shuttling in endothelial cell angiogenesis via PI3K Pathway. BBA Mol Cell Biol, 1821: 1361-1369 https://www.researchgate.net/publication/230581243_OxLDL_stimulates_Id1_nucleocytoplasmic_shuttling_in_endothelial_cell_angiogenesis_via_PI3K_Pathway
[62]	Qiu J, Wang G, Zheng Y, Hu J, Peng Q, Yin T. 2011. Coordination of Id1 and p53 activation by oxidized LDL regulates endothelial cell proliferation and migration. Ann Biomed Eng, 39: 2869-2878 doi: 10.1007/s10439-011-0382-6
[63]	Shyy J Y J, Chien S. 1997. Role of integrins in cellular responses to mechanical stress and adhesion. Cur Opin Cell Biol, 9: 707-713 doi: 10.1016/S0955-0674(97)80125-1
[64]	Sun X, Fu Y, Gu M, Zhang L, Li D, Li H, Chien S, Shyy J Y, Zhu Y. 2016. Activation of integrin ff5 mediated by flow requires its translocation to membrane lipid rafts in vascular endothelial cells. Proc Natl Acad Sci USA, 113: 769-774 doi: 10.1073/pnas.1524523113
[65]	Wan X J, Zhao H C, Zhang P, Huo B, Shen B R, Yan Z Q, Qi Y X, Jiang Z L. 2015. Involvement of BK channel in differentiation of vascular smooth muscle cells induced by mechanical stretch. Int J Biochem Cell Biol, 59: 21-29 doi: 10.1016/j.biocel.2014.11.011
[66]	Wang L, Li J Y, Zhang X Z, Liu L, Wang Z M, Li R X, Guo Y. 2012. Innvolvement of p38MAPK/NF-Kb signaling parhways in osteoblasts differentiation in response to mechanical stretch. Ann Biomed Eng, 40:1884-1894 doi: 10.1007/s10439-012-0548-x
[67]	Wang Y, Tang Z, Xue R, Singh G K, Shi K, Lv Y, Yang L. 2011. Combined effects of TNF-, IL-1, and HIF-1? on MMP-2 production in ACL fibroblasts under mechanical stretch: an in vitro study. J Orthop Res, 29: 1008-1014 doi: 10.1002/jor.21349
[68]	Wang Y X, Botvinick E, Zhao Y H, Berns M W, Usami S, Tsien RY, Chien S. 2005. Visualizing the mechanical activation of Src. Nature, 434: 1040-1045 doi: 10.1038/nature03469
[69]	Wang Z Z, Liu X, Kang H Y, Sun A, Fan Y, Deng X. 2014. Enhanced accumulation of LDLs within the venous graft wall induced by elevated filtration rate may account for its accelerated atherogenesis. Atherosclerosis, 236: 198-206 doi: 10.1016/j.atherosclerosis.2014.07.006
[70]	Wang X, Fang X, Zhou J, Chen Z, Zhao B, Xiao L, Liu A, Li Y S, Shyy J Y, Guan Y, Chien S, Wang N. 2013. Shear stress activation of nuclear receptor PXR in endothelial detoxification. Proc Natl Acad Sci USA, 110: 13174-13179 doi: 10.1073/pnas.1312065110
[71]	Wen L, Chen Z, Zhang F, et al. 2013. Ca2+/calmodulin-dependent protein kinase kinase fi phosphorylation of Sirtuin 1 in endothelium is theroprotective. Proc Natl Acad Sci USA, 110: E2420-E2407 doi: 10.1073/pnas.1309354110
[72]	Wu Y, Zhang X, Zhang P, Fang B, Jiang L. 2012. Intermittent traction stretch promotes the osteoblastic differentiation of bone mesenchymal stem cells by the ERK1/2-activated Cbfa1 pathway. Connect Tissue Res, 53: 451-459 doi: 10.3109/03008207.2012.702815
[73]	Xie J, Wang C, Huang D Y, Zhang Y, Xu J, Kolesnikov S S, Sung K L, Zhao H. 2013. TGF-beta1 induces the different expression of lysyl oxidases and matrix metalloproteinases in anterior crcuaite ligament and medial collateral ligament fibroblasts after mechanical injury. J Biomech, 46: 890-898 doi: 10.1016/j.jbiomech.2012.12.019
[74]	Xu G K, Yang C, Du J, Feng X Q. 2014. Integrin activation and internalization mediated by extracellular matrix elasticity: A biomechanical model. J Biomech, 47: 1479-1487 doi: 10.1016/j.jbiomech.2014.01.022
[75]	Yang H, Guan L, Li S, Jiang Y, Xiong N, Li L, Wu C, Zeng H, Liu Y. 2016. Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo. Oncotarget, 7: 16227-16247 https://www.researchgate.net/publication/296055323_Mechanosensitive_caveolin-1_activation-induced_PI3KAktmTOR_signaling_pathway_promotes_breast_cancer_motility_invadopodia_formation_and_metastasis_in_vivo
[76]	Yang Z, Xia W H, Zhang Y Y, Xu SY, Liu X, Zhang X Y, Yu B B, Qiu Y X, Tao J. 2012. Shear stress-induced activation of Tie2-dependent signaling pathway enhances reendothelialization capacity of early endothelial progenitor cells. J Mol Cell Cardiol, 52: 1155-1163 doi: 10.1016/j.yjmcc.2012.01.019
[77]	Yang Y C,Wang X D, Huang K,Wang L, Jiang Z L, Qi Y X. 2014. Temporal phosphoproteomics to investiate the mechanotransduction of vascular smooth muscle cells in response to cyclic stretch. J Biomech, 47:3622-3629 doi: 10.1016/j.jbiomech.2014.10.008
[78]	Zeng Y, Sun H R, Yu C, Lai Y, Liu X J, Wu J, Chen H Q, Liu X H. 2011. CXCR1 and CXCR2 are novel mechano-sensors mediating laminar shear stress-induced endothelial cell migration. Cytokine, 53: 42-51 doi: 10.1016/j.cyto.2010.09.007
[79]	Zhang P, Wu Y, Jiang Z, Jiang L,Fang B. 2012. Osteogenic responses of bone mesenchymal stem cells to continuous mechanical strain is dependent on ERK1/2-Runx2 signaling. Int J Mol Med, 29: 1083-1089
[80]	Zhang P, Wu Y, Dai Q, Fang B,Jiang. 2013. p38-MAPK signaling pathway is not involved in osteogenic differentiation during early response of mesenchymal stem cells to continuous mechanical strain. Mol Cell Biochem, 378: 19-28 doi: 10.1007/s11010-013-1589-7
[81]	Zhao F, Li L, Guan L, Yang H,Wu C, Liu Y. 2014. Roles of GP IIb/IIIa and ffvfi3 integrins in MDA-MB-231 cell invasion and shear flow-induced cancer cell mechanotransduction. Cancer Lett, 344: 62-73 doi: 10.1016/j.canlet.2013.10.019
[82]	Zhou J, Li Y S, Nguyen P, Wang K C, Weiss A, Kuo Y C, Chiu J J, Shyy J Y, Chien S. 2013. Regulation of vascular smooth muscle cell turnover by endothelial cell-secreted microRNA-126: Role of shear stress. Circ Res, 113: 40-51 doi: 10.1161/CIRCRESAHA.113.280883

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16.	李晓娜，宋一菲，史佩佩，宋婕，陈维毅，贺瑞. 机械牵拉对角膜成纤维细胞氧化应激、炎性因子和MMP-9表达的影响. 太原理工大学学报. 2019(04): 529-535 .
17.	杨金娟，陈俊飞，支子，严翊. 肌腱力学生物学与运动性肌腱损伤病理机制研究进展. 中国运动医学杂志. 2019(10): 901-906 .
18.	施兴华，张路姚，李博，冯西桥. 肿瘤及其微环境的力学问题. 力学进展. 2018(00): 360-409 . 本站查看
19.	姜宗来. 从生物力学到力学生物学的发展——为冯元桢先生百岁寿辰献礼. 医用生物力学. 2018(S1): 22-26 .
20.	陈维毅. 与疾病相关的力学生物学研究——贺冯元桢先生百岁诞辰. 医用生物力学. 2018(S1): 33-37 .
21.	杨力. 应力-生长关系与组织修复——贺冯元桢先生百岁华诞. 医用生物力学. 2018(S1): 48-53 .
22.	齐颖新. 血管力学生物学研究进展. 医用生物力学. 2018(S1): 80-84 .
23.	刘贻尧. 肿瘤细胞力学与力学生物学研究进展. 医用生物力学. 2018(S1): 85-95 .
24.	陈维毅. 2016～2018年中国生物力学研究进展. 医用生物力学. 2018(06): 477-482 .
25.	徐志玲，吕永钢，杨力，颜艳，沙永强. 应力加载系统在细胞力学研究与教学中的应用. 实验室科学. 2018(06): 119-124 .